First Author: S.Gupta INDIA
Co Author(s):
Purpose:
To study the indications and outcome of therapeutic penetrating keratoplasty (TPK) in our set-up.
Setting:
: Max Eye Care, New Delhi,India
Methods:
Retrospective review of records of 104 patients (104 eyes) who underwent TPK was carried out. Information reviewed included age, gender, indication for surgery, surgical details, post- operative complications, visual and anatomical outcome of surgery.
Results:
Mean age of patients was 45.78 ± 18.68 years. There were 81 males (77.8%), 23 females (22.1%). Indications for surgery included perforated corneal ulcer in 33.6% eyes, non healing fungal keratitis in 33.6%, non healing bacterial keratitis 20.19%, mixed infective keratitis 6.73%, non healing viral keratitis 1.92%, traumatic corneal perforation 1.92% and chemical melt 1.92%. The mean follow-up period was 18 months. Post-operatively, visual acuity remained same in 61.5% eyes. 16.3% eyes had vision ≥ 20/200. Anatomical integrity was achieved in 97.1% eyes. Three eyes were phthisical. Clear grafts were seen in 40.3% eyes. Causes of graft failure were ocular surface disease 25.0 %, graft infection 16.3%, glaucoma 7.69 %, graft rejection 5.76 % and primary graft failure 4.80%.
Conclusions:
TPK is successful in maintaining the ocular integrity. It has an important role in salvaging the eyes with active uncontrolled infection or perforation from corneal disease. Lower number of clear grafts in our study could be due to previous topical steroids misuse, late presentation, lack of availability of good quality donor tissue and inadequate compliance with follow-up.
Financial Disclosure:
No
