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Hydrogel ocular bandages used in cataract surgery: indications and results

Session Details

Session Title: Cataract I

Session Date/Time: Friday 03/02/2012 | 10:30-12:30

Paper Time: 12:09

Venue: Hall 1

First Author: : M.Piovella ITALY

Co Author(s): :    B. Kusa              

Abstract Details

Purpose:

To evaluate a new liquid hydrogel ocular bandage (OcuSeal) to cover clear corneal cataract surgical incisions. The clinical outcomes of patient discomfort (due to corneal epithelial abrasion), complications or other adverse reactions were evaluated.

Setting:

Centro Microchirurgia Ambulatoriale (CMA), Monza, Italy

Methods:

At the conclusion of cataract surgery, we applied OcuSeal liquid bandage (Beaver Visitec International) to reinforce closure of clear corneal incisions (up to 3.0 mm) in 132 eyes of 98 patients (45 males, 53 females, mean age 66.6 ±12.5). OcuSeal consists of a synthetic dentritic hydrogel comprised ot two separate components: powdered polyethylene glycol (PEG) and liquid polyethylene amine (PEI). The hydrogel is activated upon mixing and is then eaily applied as a liquid directly onto the ocular surface. After application, OcuSeal cross-links within 30 seconds to form a smooth, flexible and transparent barrier film that protects the incision. RESULTS During the immediate post-operative interval, patients treated with OcuSeal reported improved comfort. The hydrogel had irregularly dissolved or dislodged (evident by slitlamp observation) in all cases within 12 hours. No complications or adverse events were noted during the 3 month post-operative follow-up, and in particular no endophthalmitis cases developed. During the initial cases, OcuSeal was not correctly applied in 8 patients, as our inexperience in slow application of the liquid polymer to the corneal surface was not consistent with its relatively rapid polymerization.

Conclusions:

: OcuSeal liquid bandage applied at completion of cataract surgery may enhance incisional wound closure and improves post-operative patient comfort.

Financial Disclosure:

... receives consulting fees, retainer, or contract payments from a competing company