First Author: A.Gab-Alla EGYPT
Co Author(s):
Purpose:
To determine intraocular pressure (IOP) and corneal biomechanical properties in myopic subjects in Suez Canal area in Egypt.
Setting:
Population-based, descriptive study.
Methods:
Three hundred and fifty eyes(350) of Myopic patients (n = 179, age: 29.4 ± 8.9 years) with mean refractive errors of spherical equivalent (SE) + SD was -5.00D + 2.8D were recruited in this study. All subjects in this population-based study underwent a standardized ocular examinations. Metrics of corneal biomechanical properties, including corneal hysteresis (CH) and corneal resistance factor (CRF), Central corneal thickness (CCT), were measured with the Ocular Response Analyzer (ORA). The ORA also determined the values of intraocular pressure (IOPg) and corneal compensated IOP (IOPcc).
Results:
The mean Corneal hysteresis was 9.3+ 1.4 . The mean CRF was 9.7+ 1.6. The mean CCT was 535.1+ 37.7 µm. The mean IOPg 16.3+ 3.13mmHg and IOPcc 17.8+ 2.9 mmHg. The relationship between CH and CCT; CRF and CCT; CRF and CH were significant ( p < 0.0001). There is a negative correlation between CH and IOPcc, positive correlation between IOPcc and refractive errors. IOPcc measured by ORA is greater than IOPg by 11.2% (p<0.0001). The cutoff point of IOPcc is 19.2mmHg. CH and CRF decreased in aged subjects.
Conclusions:
Corneal hysteresis (CH) and corneal resistance factor (CRF) measured by the ORA have a positive but moderate correlation to CCT; the higher the CCT the higher the hysteresis (visco-elasticity) and CRF (elasticity). It may be helpful in the future for long term monitoring of glaucoma and other disease processes of the cornea. for eyes where IOP measurement is important. It may provide additional factors over and above CCT for cases in which corneal biomechanics are important and help with the assessment of the accuracy of IOP. Further studies need to be done to establish the relevance and usefulness of these measures. FINANCIAL DISCLOSURE?: No
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