Efficacy and safety of selective laser trabeculoplasty (SLT): results of this procedure for open angle glaucoma (OAG) over a 8½ year period

Poster Details

First Author: F.Ferentini ITALY

Co Author(s):    A. Porta              

Abstract Details

Purpose:

to examine safety, efficacy and tonometric outcomes of SLT procedure for patients with OAG;. Reducing the IOP values of 20% is our goal

Setting:

Eye Unit, C. Cantł Hospital, Abbiatergrasso, Milan, Italy

Methods:

We collected the results at 1 week, 1, 3, 6, 12 months and then, every 6 months up to 102 months postoperatively. We treated, with SLT procedure onto the 180° inferior trabecular meshwork, 118 eyes affected by known OAG, 99% of which Primary:53 reduced their drops after SLT; 65 did not change their previous therapy after the procedure. 12 eyes had the SLT as first line of treatment, due to the fact they have new diagnosis of OAG or OHT. Statistical analysis is performed through t-Student test for paired data

Results:

After 102 months, 45 eyes out of 118 survived; 45 eyes were excluded for post-SLT surgery, 13 excluded for changing therapy for visual field deterioration but valid IOP or loss of effectiveness of previous treatments, 15 were lost during follow-up. Their pre-operative IOP was 19.2(SD:3.2) mmHg (range 22-32). From the baseline IOP value, the IOP reduction obtained is -25.52% (p< 0.001), average 14.23 mmHg. Regarding the single groups: the IOP average was 14.27(SD:2.17) mmHG for the eyes maintaining the same therapy, 13 eyes maintained the success criteria at any single follow up time visit, 14 eyes were considered " non responders" not achieving an IOP reduction of 20% or more at least in 3 months time, 8 eyes were considered " slow responders" obtaining the success criteria only in 3 months time but not before. The IOP average was 14.66(SD:2.43) for those changing their medical treatments, 4 eyes maintained the success criteria at any single follow up time visit, 13 eyes were considered " non responders" , 6 eyes were considered " slow responders" . The 12 eyes with recent diagnosis started from an IOP average of 24.16(SD:3.9) mmHg, dropping to 15.79(SD:1.63) mmHG, (p=NA), 5 of them were excluded for post laser cataract procedure

Conclusions:

SLT shows to have an excellent efficacy and safety as replacement of or in addition to medical therapies, being a non-invasive procedure with longstanding effect. Sides effects were minimal and transient. As first-line treatment, it seems to be more effective than in eyes medically treated previously FINANCIAL DISCLOSURE?: No