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Changes in eye biomechanical properties and optic disk parameters as a result of dosed IOP increase

Poster Details

First Author: S.Anisimov RUSSIA

Co Author(s):    S. Anisimova   L. Arutyunyan   N. Chigovanina   T. Lubimova     

Abstract Details



Purpose:

Comparative analysis of optic disk parameters and corneal hysteresis (CH) data during loading vacuum-compression test were performed.

Setting:

EYE CENTER " EAST SIGHT RECOVERY" Moscow, Russia

Methods:

12 patients (19 eyes) with glaucoma suspicion were examined. During examination the dosed IOP increase (by 10 mm Hg) was achieved by special small sucker cap applied to the eye and connected to vacuum compressor with a tube. IOP increase was monitored by applanation tonometry of examined eye on Ocular Response Analyser (ORA) with the help of vacuum level regulation in system. Also CH was measured on ORA before and on different levels of loading. Structural changes of optic disk were detected by optical coherent tomography (OCT) before and after vacuum loading.

Results:

The examination performed showed that during dosed IOP growing in 36.8 % of all patients (I group) the optic disk square and neuroretinal band square increased in average on 0.73 mm and on 0.39 ??² respectively. In 63.2 % of all cases (II group) the optic disk square increased in average on 0.17 mm, but neuroretinal band square on the contrary decreased on 0.11 mm. Changes of corneal hysteresis (CH) parameters correlated with optic disk paremeters. Thus in I group of patients CH data decreased to 6.4 mm Hg while IOP increased on 5 mm Hg, and with further increase of loading up to 10 mm Hg, CH parameters increased up 9.3 mm Hg. In II group CH decreased up 7.9 mm Hg, and then up 5.6 mm Hg. The difference between the patients turned to be statistically reliable, but the data presented should be considered preliminary.

Conclusions:

OCT can evaluate optic disk changes during vacuum-compression loading. Changes in CH and optic disk parameters during dosed elevation of IOP can have diagnostic importance in cases of glaucoma suspicion. FINANCIAL DISCLOSURE?: No

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