Comparison of endothelial cell loss in DALK with intact Descemet membrane and microperforation

Poster Details

First Author: B.Torun Acar TURKEY

Co Author(s):    E. Turan Vural   S. Acar           

Abstract Details

Purpose:

To compare the endothelial cell loss in DALK with intact Descemet membrane and microperforation

Setting:

Haydarpasa Numune Education and Research Hospital, Ophthalmology Clinic, Istanbul, Turkey

Methods:

Hundred and thirty-eight eyes of 124 patients who underwent DALK using the big-bubbletechnique were included in this retrospective study. Patients were evaluated and divided into two groups according to Descemet membrane. Hundred and twenty eyes were in group 1 with intact Descemet membrane, and 24 eyes were in group 2 who had microperforation during surgery. Endothelial cell density was analyzed using non-contact specular microscopy preoperatively, 3, 6, and 12 months after surgery.

Results:

The change in ECDs was significantly higher in Group 1 compared to Group 2, from preoperative measurement to postoperative 3st month, from 3rd to 6th month and 6th to 12th month (p < 0.01 for all).

Conclusions:

Eyes with microperforation had significantly greater loss of ECD compared to eyes with intact Descemet membrane. Surgery should be done more carefully to avoid Descemet membrane perforation. FINANCIAL DISCLOSURE?: No