Posters

Evaluations of corneas in eyes with isolated iris coloboma

Poster Details

First Author: A. Karatepe Hashas TURKEY

Co Author(s):    H. Arifoglu   Y. Yuce   N. Duru   D. Ulusoy   G. Zararsiz        

Abstract Details

Purpose:

We aimed to evaluate the differences in the corneas of eyes with isolated iris coloboma

Setting:

This study was designed as a prospective study.

Methods:

Among patients who applied to our hospital within the last three-year period, those with isolated iris coloboma in one eye and a completely normal contralateral eye were included in the study. In addition to a complete ophthalmologic examination, all patients were scanned by Pentacam Scheimpflug camera in the dark, and a corneal endothelium cell count was taken using a Topcon Specular Microscope. Data entered using SPSS software were then evaluated by paired t-test; p < 0.05 value was considered statistically significant.

Results:

Nine patients with a mean age of 35.77±22.50 years were included in the study. In comparison to normal eyes, the colobomatous eyes were statistically found to have lower keratometry values (43.82±2.17, 44.46±1.86;p=0.040), a greater negative asphericity (-0.38±0.07, -0.22±0.20; p=0.042), increased corneal thickness (569.78±25.42, 537.33±27.36; p<0.001), decreased anterior chamber depth (2.50±0.32, 2.81±0.50; p=0.005), a shallower angle (30.51±10.68, 35.29±9.99; p=0.057), higher BFS (best-fit sphere) values of the anterior and posterior corneal surfaces (7.88±0.39, 7.67±0.37; p=0.001; 6.40±0.26, 6.23±0.19; p=0.006), smaller horizontal corneal diameter (11.06±0.42; 11.26±0.45; p= 0.009) and higher value of endothelial cell density (3161±431; 2923±590; p=0.031).

Conclusions:

We have determined that a number of factors such as keratometry values, particularly of the corneal endothelium, are different from those of normal eyes. These differences should be taken into account in the follow-up and treatment of eyes with iris coloboma.

Financial Disclosure:

NONE