Posters

Diabetic corneal and refraction study

Poster Details

First Author: P. Chong MALAYSIA

Co Author(s):    A. Loo                    

Abstract Details

Purpose:

To investigate the effect of diabetes on cornea and refraction among subjects attending eye clinic.

Setting:

Topvision Eye Specialist Center

Methods:

In this clinic based observational cross sectional study, one hundred fifty six diabetic and one hundred fifty control subjects were enrolled randomly. Best corrected visual acuity (BCVA), autorefraction, keratometry, corneal pachymetry and ultrasonic biometric measurements of the right or better seeing eye were measured and analyzed statistically. Diabetic control (HbA1C level) and duration of diabetes were used as independent variables.

Results:

Most diabetics had poor glycaemic control with mean (SD) HbA1C 8.09 ± (1.6) %. Multiple linear regression analysis showed significant positive correlation between K reading (KR) and diabetes mellitus (r=0.360 {95% CI=0.049, 0.671}, p=0.023) in which diabetics had significantly steeper KR (44.58 ± 1.38D, p=0.017). Mean central corneal thickness (CCT) in diabetics appeared thicker (572.88 ± 35.93 µm, p=0.064) when compared to control (565.31 ± 35.40 µm) but it did not reach statistical significance.

Conclusions:

Diabetes mellitus and its duration had no significant effect on best corrected visual acuity, axial length (AL) or spherical equivalent (SE).

Financial Disclosure:

NONE