Posters

Diagnostic and therapeutic management of Lisch corneal distrophy

Poster Details

First Author: A. Ruiz-Alcantara SPAIN

Co Author(s):    J. Gallardo-Galera   M. Sanchez-Frias   R. Garcia-Catalan              

Abstract Details

Purpose:

To report the clinical findings, anterior segment optical coherence tomography (AS-OCT) , confocal microscopy, histopathology and electron microscopy in a patient affected by Lisch epithelial corneal distrophy.

Setting:

Ophthalmology department. Reina Sofía University Hospital, Córdoba, Spain.

Methods:

Case report.

Results:

We report a 56-year-old woman who presented with a painless loss of visual acuity in the left eye of 3-month duration. A grayish, comet-shaped and feathery corneal opacification involving the visual axis was located in corneal epithelium. Retroillumination showed intraepithelial, crowded microcysts. After confocal microscopy and AS-OCT, Lisch corneal dystrophy was suspected and an alcohol-facilitated epitheliectomy was performed. The histopathologic and electron microscopic studies confirmed the diagnosis. Visual acuity improved after the epithelial scraping. However, the lesion recurred one year later.

Conclusions:

Lisch dystrophy is uncommon. Confocal microscopy is a useful diagnostic tool and diagnosis is confirmed by histological analysis. The recurrence after epithelial debridement makes us consider other treatment options such as surface ablation with mitomycin C in future interventions.

Financial Disclosure:

NONE