Posters

Tumor necrosis factor-alpha and interleukin-10 in aqueous humor and serum of patients with pseudoexfoliation syndrome

Poster Details

First Author: R. Sorkhabi IRAN, ISLAMIC REPUBLIC OF

Co Author(s):    M. Ahoor                    

Abstract Details

Purpose:

The aim of the present study was to determine the levels of inflammation related cytokines in the aqueous humor and serum of patients with pseudoexfoliation syndrome.

Setting:

tabriz university of medical sciences

Methods:

In this study we measured the level of inflammatory markers such as Tumor Necrosis Factor-alpha, Interleukin-10 in the aqueous humor and serum of 30 patients with pseudoexfoliation syndrome and compared the results with 30 healthy controls.

Results:

Results:Aqueous humor obtained from patients with pseudoexfoliation syndrome showed increased levels of Interleukin -10 and Tumor Necrosis Factor-alpha (p=0.01, p=0.002). The serum levels of Interleukin-10 and Tumor Necrosis Factor-alpha in pseudoexfoliation syndrome group was significantly higher than those of the control group(p=0.01, p=0.001)

Conclusions:

Pseudoexfoliation syndrome is associated with molecular inflammatory response in aqueous humor and serum.

Financial Disclosure:

NONE