Posters
Serum vitamin D level in patients with pseudoexfoliation syndrome and pseudoexfoliative glaucoma
Poster Details
First Author: W. Shihadeh JORDAN
Co Author(s): M. Belal M. Al-Hashimi A. Al-Dabbagh S. Jaradat Y. Khader
Abstract Details
Purpose:
To compare the level of serum vitamin D in patients with pseudoexfoliation syndrome (XFS) and pseudoexfoliative glaucoma (XFG) with that in control subjects. Moreover, to compare the associated systemic diseases in the two groups
Setting:
Jordan University of Science & Technology
King Abdullah University Hospital
JORDAN
Methods:
Serum levels of 25-hydroxy vitamin D [25(OH) D] were measured using liquid chromatography. Variables like age, sex and medical history of hypertension, diabetes mellitus and ischemic heart disease were reported. Measurements of vitamin D level were classified as normal (20-70 ng/ml), insufficient (10-less than 20 ng/ml) and deficient ( less than 10 ng/ml).
Results:
This study included a total of 55 patients with XFS/XFG and 60 subjects control subjects. Patients with XFS/XFG were significantly older than control subjects (mean age; 71.8 vs. 67.5 year, p-value = 0.002). Gender distribution was similar for the two groups. The prevalence rates of diabetes, hypertension, and ischemic heart disease were not significantly different.The mean of 25-hydroxy vitamin D was 14.7 ng/mL for patients with XFS/XFG and 14.9 ng/mL for control subjects with no significant difference. The prevalence rate of vitamin D deficiency at different levels of 25-hydroxy vitamin D was not significantly different. Multivariate analysis did not show significant difference in vitamin D deficiency between the two groups after adjusting for age, gender, and medical conditions.
Conclusions:
Vitamin D levels were low in both the XFS/XFG group and the control group being lower in the first one but with no significant difference. The prevalence rates of systemic diseases were not significantly different between the two groups.
Financial Disclosure:
NONE
