Posters

Prognostic factors for lowering IOP in primary open-angle glaucoma (POAG) by combined supraciliary microstenting-phaco cataract surgery: COMPASS RCT

Poster Details

First Author: T. Ianchulev UNITED STATES

Co Author(s):    B. Flowers   M. Packer   F. Tyson   Q. Nguyen   S. Sarkisian   S. Vold     

Abstract Details

Purpose:

To evaluate prognostic factors for reducing IOP by supraciliary stenting (CyPass) in POAG patients having cataract surgery.

Setting:

Multi-site US Clinical Study

Methods:

POAG subjects (N=505) having cataract surgery were randomized to phaco (Control; n=131) or microstenting + phaco (Stent; n=374) groups (1:3 ratio). We assessed IOP and medication use during postoperative 12 month.

Results:

Control and Stent respective baseline mean IOPs were 24.5±2.95 and 24.4±2.77 mmHg, and preop mean medications were 1.3±1.0 and 1.4±0.9. The 12-month IOP reductions were 25.5% and 31.7%, mean meds were 0.7±0.9 and 0.2±0.5, and the proportion of patients on no medications were 52.3% and 89.0%, respectively. Therapeutic response did not differ by patient age, gender, or baseline IOP and medications.

Conclusions:

Supraciliary microstenting better reduced IOP and postop medication use in multiple subgroups vs phaco controls.

Financial Disclosure:

One or more of the authors receives consulting fees, retainer, or contract payments from a company producing, developing or supplying the product or procedure presented, One or more of the authors research is funded, fully or partially, by a competing company, One or more of the authors research is funded, fully or partially, by a company producing, developing or supplying the product or procedure presented, One or more of the authors receives consulting fees, retainer, or contract payments from a competing company