Posters

Assessment of peri-papillary retinal verve fiber layer thickness in myopic Egyptians

Poster Details

First Author: A. Gab-Alla EGYPT

Co Author(s):    H. Al-Nahas   M. Shaheen   H. Akl              

Abstract Details

Purpose:

To evaluate the relation between retinal nerve fiber layer and axial lengths in otherwise healthy myopic Egyptians.

Setting:

Suez Canal University and Egyptian Eye Academy center

Methods:

80 eyes of Egyptian healthy subjects, 42 males and 38 females, ranging ( 25 to 45 years). Divided into two groups; each includes 40 eyes, according to the spherical equivalent and axial length of the patients, Group (A) low to moderate myopia (-0.5D to -6.00D) and axial length between 24-26mm. and Group (B) high myopia (-6D to -12D) and axial length greater than 26mm. Total average and mean clock hour RNFL thicknesses were measured by OCT and compared between the two myopia groups. Associations between RNFL measurements and axial length and spherical equivalent were then evaluated by linear regression analysis.

Results:

There were significant higher values of inferior and nasal retinal nerve fiber layer thicknesses in group A than in group B, whereas group B showed significant higher thicknesses at the temporal quadrant. The average retinal nerve fibers layer thickness became thinner as the axial length increased (r = −0.506, p < 0.0001). As the axial length increased, the average RNFL thicknesses in the superior, Inferior and nasal quadrants significantly decreased(r=-0.6, r=-0.6 and r=-0.3 respectively) but the temporal quadrant significantly increased(r=0.2).

Conclusions:

Peripapillary RNFL thickness changes differently in different peripapillary locations as axial length increases in myopic Egyptians. Careful interpretation of RNFL data on moderate to highly myopic individuals should be considered. Many studies should be conducted to increase the normative data of RNFL thickness to provide better sensitivity and specificity for glaucoma detection

Financial Disclosure:

NONE