Posters

Twenty-four hour phasing of intraocular pressure in Indian population with open-angle glaucoma: results of a prospective hospital-based study

Poster Details

First Author: E. Ah-kee UNITED KINGDOM

Co Author(s):    V. Shankar   A. Shukla   L. Lim              

Abstract Details

Purpose:

To study the variation in intra-ocular pressure (IOP) during a 24-hour period in patients with open angle glaucoma (OAG) in a prospective hospital-based study.

Setting:

Kasturba Hospital, Mahatma Gandhi Institute of Medical Sciences, Sewagram, India

Methods:

All patients above the age of forty presenting to the eye clinic were screened for OAG for a period of twelve months. Intra-ocular pressure was measured by applanation tonometry. Automated visual field 24-2 along with optic disc assessment and fundus photograph were also performed to assess visual fields and disc parameter measurements respectively. All patients with a diagnosis of OAG or suspected OAG underwent twenty-four hour phasing of intraocular pressures.

Results:

A total of 5385 patients above the age of forty were screened, of which 118 patients were identified as having confirmed OAG. 87 subjects were included in the study after exclusion and inclusion criteria were applied. Prevalence of OAG was 2.19 in the general population and 13.9 in the diabetic population. The mean intraocular pressure (mmHg) in the right and left eye was 14.18 ±4.57 and 14.51 ±4.6 respectively in the general population, 21.82 ±9.86 and 23.11±9.41 in patients with OAG, 14.28 ±5.09 and 14.8± 5.3 in the diabetic population, and 17.4 ±3.73 and 18.76±3.87 in the diabetics with OAG.

Conclusions:

The study showed that mean IOP in patients with OAG remains much higher compared with the general population and that IOP increases with age. Our results are comparable to previous large-scale studies. There was a significantly higher prevalence of OAG in the diabetic population compared to the general population. However, there are still conflicting reports regarding the association of diabetes and OAG. Nonetheless, it is clear that in the diabetic OAG population, optic nerve damage occurs at lower IOP compared to the non-diabetic OAG population. Hence, we believe that diabetic patients should be screened for OAG to reduce its incidence.

Financial Disclosure:

NONE