Posters

Refractive effect after FS-LASIK and SMILE, is there any correlation with corneal volume and biomechanical property?

Poster Details

First Author: Y. Wang CHINA

Co Author(s):    P. Wei   J. Zhang                 

Abstract Details

Purpose:

To investigate the potential influence of corneal volume and biomechanical property on refraction changes after small incision lenticule extraction (SMILE) and femtosecond laser–assisted laser in situ keratomileusis (FS-LASIK)

Setting:

Tianjin Eye Hospital & Eye Institute, Tianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin Medical University, Tianjin, China.

Methods:

A total of 98 eyes that underwent SMILE and FS-LASIK was followed up at 3 months postoperatively. The corneal volume (CV) obtained with Pentacam within 5 mm measurement diameter was defined as central area (CV5), and the diameter from 5 to 10 mm of CV was defined as peripheral area (CV5-10). In addition, corneal hysteresis (CH) and corneal resistance factor (CRF) were obtained with Ocular Response Analyzer (ORA). Statistical significance of CV between above procedures was evaluated by independent-samples t test. Pearson correlation was applied to analyze the correlation between acquired spherical equivalent refraction (△SE), △CRF, △CH, and △CV.

Results:

The CV were decreased significantly after both procedures (p<0.05). Significant difference was revealed in the variations of CV from 1 day to 3 months with the value of 0.11±0.16mm3 and 0.20±0.13mm3 in SMILE and FS-LASIK, respectively (p<0.05). The SE at 1 day was significant larger than other follow-ups after FS-LASIK, however, SE got stable after SMILE over times. At 3 months follow-up, the △CV5 showed negative correlations with △SE in SMILE (r=-0.756) and FS-LASIK (r=-0.798), and it was correlated with △CRF (r=0.551) and △CH (r=0.436) in SMILE, however in FS-LASIK it was only correlated with △CRF ( r=0.363).

Conclusions:

Corneal volume was changed over time after both SMILE and FS-LASIK. Corneal biomechanics were affected by the variations of CV after surgery, which maybe have correlation with refractive changes, or even refractive regression.

Financial Disclosure:

NONE