Posters

To study and analyse the factors affecting the outcome of corneal collagen cross-linking (CXL) in eyes with keratoconus

Poster Details

First Author: B. Bagga INDIA

Co Author(s):    P. Kumar   P. Kumar   M. Taneja   R. Dhakal           

Abstract Details

Purpose:

To study the effect of preoperative factors on the outcome of corneal collagen cross linking in eyes with Keratoconus in terms of regression, stabilization and progression.

Setting:

Cornea Services Taj Kohli Cornea Institute L.V.Prasad Eye institute Hyderabad, India

Methods:

Medical records of patients with Keratoconus who underwent CXL from 2010 to 2013 were reviewed retrospectively. Eyes with associated ocular co-morbidity or where other refractive procedure was performed along with CXL and follow-up period less than 6 months were excluded from the study. The demographic, clinical and topographical (Bausch & Lomb’s Orbscan IIz Topographer) details of these patients were obtained at all visits. Three post-surgical follow up visits were considered with six months interval. Effect of age of the patient, maximum keratometry value (Kmax), thinnest corneal pachymetry value and cone location on the topography map was assessed on the outcome.

Results:

205 eyes of 165 patients were included while 132 eyes analysed. There were 3 groups divided based on the age of patients. Group 1(N=39), Group 2(N=60), and Group 3 (N=39) had patients according to age 10-15, 15-20 and above 20 years respectively. These were reclassified based on Kmax, location and severity of cone. Group 1 associated with ‘central’ cone (central 3 mm zone) and showed a significant reduction in Kmax value (-3.42 D, p<0.01) from the baseline to the first year post-operative period whereas, a significant increase in keratometry (1.5 D, p<0.01) was seen in cases with ‘Para central’ cone.

Conclusions:

Variables such as the age at performing the procedure and the cone location on the topography map appears to be having an influenceover the outcome of collagen cross linking procedure. An age group of 15-20 yrs and a location of the apex of cone within the central 3 mm zone in the topography map appear to be a better predictor for the outcome of the procedure.

Financial Disclosure:

NONE