Posters

Novel clinical application of dry, processed, amniotic membrane allograft transplant during pterygium surgery

Poster Details

First Author: H. Uy PHILIPPINES

Co Author(s):    K. Kenyon                    

Abstract Details

Purpose:

To determine the effectiveness and safety of processed amniotic membrane allograft transplantation (AMT) among eyes undergoing pterygium surgery.

Setting:

Ambulatory surgical center (Peregrine Eye and Laser Institute, Makati, Philippines)

Methods:

Prospective, non-comparative, interventional case series. Twenty eyes of 18 patients with primary (15) or recurrent (5) pterygia underwent pterygium surgery. After dissection to bare sclera, excision of the pterygium head, and application of mitomycin-C, processed AMT (Amnio Tek, ISP Surgical, Methuen, MA, USA) was applied over the corneal defect and scleral bed. The AMT was kept in place using bandage soft contact lenses and conjunctival wing sutures, which were all removed after 2 weeks. Main outcome measures were: AMT integrity, epithelialization, patient comfort, recurrence rate and postoperative complications

Results:

Postoperatively, AMT remained intact in all patients. Complete epithelialization over the transplanted membrane was observed after bandage contact lens removal at 2-3 weeks. All patients demonstrated early resolution of ocular inflammation and reported minimal to no ocular discomfort. Neither pterygium recurrences nor complications were observed following processed AMT allografting

Conclusions:

Processed dry AMT demonstrated excellent biocompatibility on the human ocular surface. This new biomaterial may be a promising alternative to conjunctival grafting for the treatment of pterygium.

Financial Disclosure:

One or more of the authors gains financially from product or procedure presented