Posters

Corneal transplantations at the 1st Department of Ophthalmology, AHEPA University Hospital during the period September 2011 to January 2016: an audit

Poster Details

First Author: D. Kapantais GREECE

Co Author(s):    A. Chranioti   A. Lioura   K. Marinopoulos   K. Stamoulas   A. Kiana   N. Ziakas     

Abstract Details

Purpose:

To report the leading indications, techniques, complications and visual outcomes of corneal transplantations from September 2011 to January 2016.

Setting:

1st Department of Ophthalmology, AHEPA University Hospital, Thessaloniki, Greece.

Methods:

Retrospective data of 307 corneal transplantations performed at AHEPA University Hospital were reviewed. Indications were classified into nine different groups: Pseudophakic bullous keratopathy, ectasias (keratoconus, keratoglobus), previous graft rejection, Fuchs’ keratopathy, corneal scar (post-traumatic or chemical), microbial keratitis (bacterial and fungal), herpetic keratopathy, corneal dystrophy and other.

Results:

The leading indications for corneal transplantations were:Pseudophakic bullous keratopathy (n=89[28.99%]), ectasias (n=65[21,17%]), previous graft rejection (n=49[15.96%]), Fuchs’ keratopathy (n=37[12.05%]), corneal scar (n=20[6.51%]), microbial keratitis (n=16[5.21%]), herpetic keratopathy (n=11[3.58%]), corneal dystrophy (n=6[1.95%]) and other (n=14[4.56%]). The most preferred transplantation technique remains penetrating keratoplasty(PK) (n=254[82.74%]) followed by Descemet's stripping endothelial keratoplasty(DSAEK-DSEK) (n=40[13.03%]), Descemet's membrane endothelial keratoplasty(DMEK) (n=7[2.28%]) and Deep anterior lamellar keratoplasty(DALK) (n=6[1.95%]). Mean best-corrected visual acuity(BCVA) was 1/10 preoperatively and improved to 2.3/10 post-operatively with an average follow-up of 16.97 months. The commonest complications were:Graft rejection (n=17[5.54%]), graft failure (n=14[4.56%]), glaucoma (n=4[1.30%]), iridocorneal adhesions (n=4[1.30%]), partially detached graft (n=3[0.98%]) and other (n=6[1.95%]).

Conclusions:

Pseudophakic bullous keratopathy still remains the leading indication for corneal transplantation. Ectasias, previous graft rejection and Fuchs’ keratopathy have also remained consistent indications for keratoplasty during the last 5 years. Concerning the lamellar keratoplasty procedures, DSEK-DSAEK increased from 0% in 2010 to 13.03%, while DMEK and DALK increased from 0% to 2.28% and 1.95%, respectively. As far as the visual outcome is concerned, the patients gained a mean of 7 letters on the Snellen chart at a mean follow-up of 16.97 months. Complications were noted in the 15.64% of keratoplasties with graft rejection and graft failure being the commonest.

Financial Disclosure:

NONE