Posters
Prevention of cystoid macular edema after phacoemulsification cataract surgery
Poster Details
First Author: E. Stangogianni GREECE
Co Author(s): C. Stangogianni
Abstract Details
Purpose:
To determine whether nepafenac ophthalmic suspension 0.1% plus dexamethasone 0.1% ophthalmic suspension, effectively decreases the incidence of Cystoid Macular Edema, inflammation and pain that occur after cataract surgery.
Setting:
Laserlens. Ophthalmology Institute, Ioannina, Greece
Methods:
Prospective, comparative, interventional and randomized study. We included 100 eyes of 100 patients that required phacoemulsification with intraocular lens and uncomplicated cataract surgery. Patients were randomly divided into two groups: first group included topical Nepafenac 0.1% + dexamethasone ophthalmic suspension 0.1%. Second group included dexamethasone ophthalmic suspension 0.1%. All patients received a standard regimen of moxifloxacin 0.5%. Ocular pain was scored on 4-point scale. Patients were evaluated postoperatively on days 1, 7, 30 and 90. At those visits, symptoms of ocular pain, ocular discomfort and visual complaint were also recorded. On day 30 and 90 optical coherent tomography was performed.
Results:
The mean age was 65 years (range 42 to 85 years). Presence of flare in both group was found in 100% of the patients the first 24 hours. The intraocular pressure average was of 13.04 mmHg at 24 hours and it was maintained without significant changes through the study. Until the seventh postoperative day, 12.5% of patients presented sensation of foreign body that diminished to the 5% around the forth week. No CME developed in group 1; 2 cases were found with OCT examination 3 month after surgery and corroborated the CME with fluorescent angiography in group 2.
Conclusions:
The combination of nepafenac non steroidal anti-inflammatory plus dexamethasone 0.1% ophthalmic suspension reduced de incidence of CME and inflammation in patients with uncomplicated cataract surgery
Financial Disclosure:
NONE
