Continuous 24-hour monitoring of ocular dimensional changes using the Triggerfish contact lens sensor in patients undergone canaloplasty surgery

Session Details

Session Title: Glaucoma II

Session Date/Time: Monday 12/09/2016 | 08:00-10:30

Paper Time: 08:24

Venue: Hall C4

First Author: : A.Byszewska POLAND

Co Author(s): :    M. Rekas   M. Danielewska   K. Petz   J. Wierzbowska   D. Iskander        

Abstract Details

Purpose:

To ascertain whether 24-hour continuous monitoring of corneoscleral limbus area (CSLA) with the Triggerfish Contact Lens Sensor (TF-CLS) can be clinically utilized for assessing long-term efficacy of canaloplasty.

Setting:

Department of Ophthalmology, Military Institute of Medicine, Warsaw, Poland

Methods:

Ten patients with POAG underwent canaloplasty and cataract extraction. Eyes not previously operated were included with pre-op washout. BCVA, IOP, anterior and posterior segments of the eye, number of medications were examined. Follow-up examinations were done on days 1, 7 and at 1, 3, 6, and 12 months. Apart from standard clinical data, there were collected 10 pre-op records with TF-CLS. Raw TF-CLS signals were numerically analysed to lead the best-sine wave fit. Two parameters were considered: the amplitude of the fitted sine-wave and the overall root mean square (RMS). Statistical analysis included standard descriptive statistics and paired t-test.

Results:

Mean pre-operative IOP was reduced from 20.6 ±4.71 to 14.2±3.03 (p<0.05) on 0.1±0.33 antiglaucoma medication, which equals to 31% IOP reduction. BCVA improved significantly. Diurnal changes in Triggerfish signal amplitude assumed to be equivalent to changes in ocular pulse amplitude. A post-op decrease in CSLA signal amplitudes was observed. Statistically significant differences between the pre-op and 3 month post-op for both the amplitude RMS and the sine-wave amplitude (paired t-test, p=0.022 and p=0.041, respectively) as well as between the pre-op and 12 month post-op results (p=0.043 and p=0.026, respectively) were found. No statistically significant differences were found between the 3 and 12 month post-op results for both amplitude RMS and the sine-wave amplitude (p=0.296 and p=0.170, respectively).

Conclusions:

A sine-wave pattern of continuous 24-hour CSLA signals can be used to monitor efficacy of canaloplasty

Financial Disclosure:

NONE