Effect of pupil size on visual performance with small-aperture corneal inlay

Session Details

Session Title: Corneal Inlays for Presbyopia Correction

Session Date/Time: Sunday 11/09/2016 | 16:30-18:00

Paper Time: 16:54

Venue: Hall C1

First Author: : S.Schallhorn USA

Co Author(s): :                        

Abstract Details

Purpose:

To evaluate the effect of photopic and mesopic pupil size on visual acuity and visual symptoms in emmetropic presbyopes 12 months after implantation of a small-aperture corneal inlay in the non-dominant eye for the treatment of presbyopia.

Setting:

Prospective, non-randomized multi-center study

Methods:

Photopic and mesopic pupil sizes were measured in 154 subjects using a pupilometer to the nearest half-millimeter. Uncorrected visual acuities at distance (UDVA) and near (UNVA) were measured in ETDRS letters. Visual symptoms of glare, halos and night vision were rated by subjects from 0 (none) to 7 (very severe). For analyses, photopic and mesopic data sets were each divided into two groups based on pupil diameter: greater than average (group 1) and less than or equal to average (group 2). Further, a large pupil size group was defined as being two or more standard deviations (SDs) above average.

Results:

Mean photopic and mesopic pupils were 4.4±0.88mm and 5.9±0.93mm. UDVA for photopic pupil size groups 1 and 2 were 49.8±4.8 and 50.9±4.3 letters, respectively, and UNVA were 41.0±7.1 and 42.2±8.1 letters, with no between-group differences (p=0.14 for distance and 0.34 for near). For mesopic pupil groups 1 and 2, the mean severity of halos was 1.1±1.4 and 0.83±1.5, glare 0.92±1.3 and 0.64±1.3 and night vision 0.87±1.3 and 0.99±1.6, and the between-group differences were not statistically significant (p=0.32, 0.18 and 0.61, respectively). In subjects with the largest pupils (about 5%), acuity was 2-3 letters and symptoms were 1 rating level worse.

Conclusions:

Pupil size has none to minimal impact on visual acuity and visual symptoms in the eye implanted with the small-aperture corneal inlay. Subjects with the largest pupils tended to show slightly worse outcomes, however, these trends were not statistically or clinically significant.

Financial Disclosure:

... receives consulting fees, retainer, or contract payments from a company producing, developing or supplying the product or procedure presented