Five and ten year results with the Artisan myopia phakic intraocular lens: long-term visual function, efficacy, safety and endothelial cell loss

Session Details

Session Title: Keratoconus and Phakic IOLs

Session Date/Time: Monday 12/09/2016 | 16:30-18:30

Paper Time: 17:45

Venue: Hall C4

First Author: : S.Jonker THE NETHERLANDS

Co Author(s): :    A. Ronden   T. Berendschot   I. Saelens   N. Bauer   R. Nuijts        

Abstract Details

Purpose:

Retrospective evaluation of visual and refractive parameters, efficacy, safety and endothelial cell loss in a large group of patients five and ten years after implantation with the Artisan phakic intraocular lens (pIOL) for myopia.

Setting:

Academic Center for Refractive Surgery, University Eye Clinic Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands.

Methods:

Data from all myopic patients implanted with the Artisan pIOL (Ophtec, Groningen, the Netherlands) from 1998 until present time were collected for retrospective analysis. Mean preoperative age was 41.24±10.72. 179 patients (329 eyes), 84 patients (153 eyes) and 71 patients (127 eyes) completed a follow-up of 1, 5 and 10 years respectively. Both visual and refractive, topographic and intraocular parameters and endothelial cell density were measured preoperatively, 1 day, 1 week, 1, 3, 6 and 12 months postoperatively, followed by annual visits after completing the first year follow-up.

Results:

Mean LogMAR UDVA was 0.18±0.24, 0.25±0.27 and 0.29±0.31 LogMAR respectively 1, 5 and 10 years postoperatively (p<0.01). Mean LogMAR CDVA was 0.03±0.16, 0.05±0.14 and 0.10±0.23 LogMAR 1, 5 and 10 years postoperatively (p=27 and p=0.01). Mean spherical equivalent (SE) was -0.53±0.70 D, -0.91±1.11 D and -1.36±1.46 D respectively 1, 5 and 10 years postoperatively (p<0.01). After 1, 5 and 10 years, 79%, 61% and 32% of eyes were within 1.0 D of the intended correction. Mean chronic EC loss from 6 months to 5 and 10 years postoperatively was -4.47%±1.49 and -11.31%±1.63 respectively (p<0.01).

Conclusions:

Over 10 years, uncorrected visual acuity showed a slight decline of 0.11 LogMAR due to a mean myopisation of -0.83 D. Best corrected visual acuity remained stable during 5 and 10 year follow up. There was a progressive annual endothelial cell loss of -1.13% that almost doubled the expected physiological endothelial cell loss of -0.6% per year.

Financial Disclosure:

NONE