Tilted optic disc lamina cribosa configuration in patients with and without ocular hypertension or glaucoma

Session Details

Session Title: Glaucoma II

Session Date/Time: Monday 12/09/2016 | 08:00-10:30

Paper Time: 08:52

Venue: Hall C4

First Author: : A.Miranda PORTUGAL

Co Author(s): :    S. Parreira   S. Barros   P. Telles   N. Campos           

Abstract Details

Purpose:

Lamina cribosa (LC) is considered the primary axonal lesion location in glaucoma. Studies have concluded that LC is posteriorly displaced in glaucoma patients and that influences the rate of retinal nerve fiber layer (RNFL) thinning. Glaucoma clinical diagnosis in patients with tilted discs may be difficult, and complementary methods are particularly usefull. The purpose of this study was to determine the anterior lamina cribrosa surface depth (ALCSD) in eyes with tilted discs with and without ocular hypertension (OHT) or glaucoma.

Setting:

Hospital Garcia de Orta, EPE.

Methods:

Cross-sectional study, including 69 eyes with tilted disc, separated in two groups: group one with 40 eyes with OHT or glaucoma and group two with 29 eyes without OHT or glaucoma. Images from optic disc horizontal and vertical sections were obtained using spectral domain optical coherence tomography (SD-OCT) and ALCSD was calculated in each image. The maximum vertical and horizontal values were used for statistical analysis.

Results:

69 eyes were included, from patients with a mean age of 70,07±11,42 and 71,24±10,20 years respectively in group one and two. Mean horizontal ALCSD was 412,67±145,06 μm in group one and 279,71±154,32 μm in group two (p<0,001) and mean vertical ALCSD was 397,95±148,94 μm in group one and 239,56±124,64 μm in group two (p<0,001).

Conclusions:

This study concluded that there is a statistical significant difference in ALCSD in tilted discs between patients with or withou OHT or glaucoma. Therefore longitudinal optic disc study throught SD-OCT can complement initial clinical evaluation of these patients and, eventually, be usefull in their follow-up.

Financial Disclosure:

NONE