Effects of atopic syndrome on keratoconus manifestation

Session Details

Session Title: Cornea Medical I

Session Date/Time: Monday 12/09/2016 | 17:00-18:30

Paper Time: 18:06

Venue: Hall C2

First Author: : M.Shajari GERMANY

Co Author(s): :    E. Eberhardt   G. Al Khateeb   M. Müller   M. Remy   T. Kohnen        

Abstract Details

Purpose:

To evaluate effects of atopic syndrome on manifestation of keratoconus

Setting:

Department of Ophthalmology, University of Frankfurt, Germany

Methods:

In this retrospective study we reviewed patient files and data generated by Scheimpflug imaging of 670 eyes of 434 keratoconus patients. Patients were divided into a study group consisting of patients suffering of atopic syndrome (110 eyes of 75 patients), namely allergic asthma, atopic dermatitis and/or allergic rhinitis and a control group with patients without known atopic syndrome (560 eyes of 359 patients).

Results:

We found a significant difference with the mean age being 36.07 ±11.70 for the control group, 32.76 ±9.58 for the atopic group (P=0.002) with one atopic trait and 30.40 ±7.53 for patients with two or more atopic traits (P=0.002). No statistically significant differences were found in the mean corrected distance visual acuity, corneal pachymetry, minimum relative pachymetric progression (RPI min), mean refraction, keratoconus index (KI), Kmax and location of Kmax. However, However, we found a significantly higher corneal density for the anterior 120µm of the cornea in the atopic group (control: 20.74 ±4.68, atopic group: 21.92 ±4.65 P=0.016).

Conclusions:

Keratoconus patients suffering from atopic syndrome were significantly younger but showed no topographical changes except in corneal densitometry compared to keratoconus patients without an atopic disease. This suggests atopic syndrome is a factor which can trigger an earlier manifestation of keratoconus.

Financial Disclosure:

NONE