Allogenic corneal inlays and onlays

Session Details

Session Title: Corneal Inlays for Presbyopia Correction

Session Date/Time: Sunday 11/09/2016 | 16:30-18:00

Paper Time: 17:36

Venue: Hall C1

First Author: : M.Mrochen SWITZERLAND

Co Author(s): :    D. Muller                    

Abstract Details

Purpose:

Epikeratophakia and more recently endokeratophakia have been used for refractive corrections. However, these to techniques are plagued with specific limitation to be used on a routine basis. The purpose of this work is to demonstrate the feasibility of providing onlays and inlays utilizing modern technology to achieve the creation of precise and repeatable lenticules from sterile corneal tissue to overcome the limitations of epikeratoplasty and endokeratoplasty.

Setting:

Allotex inc. Boston, USA

Methods:

Porcine corneas was delaminated by means of a laboratory femtosecond laser into multiple layers of corneal sheets with a target thickness of 30 micron and the thickness of each layer was measured by means of OCT scans. In addition, available human corneal sheets with a shelf lifetime of 1 year were photoablated by means of a commercially available excimer laser (EyeQ , WaveLight, Erlangen, Germany). The resulting spherical shape was measured by OCT to determine the shape of the achieved lens.

Results:

Cornea tissue can be delaminated into up to 10 corneal sheets with a predetermined thickness and diameter. Utilizing an excimer laser, we were able to create lens shaped human corneal lenses with reliable precision.

Conclusions:

Currently available technology is suitable to create corneal inlays or onlays and has the potential to overcome the limitations of epikertophakia and endokertophakia.

Financial Disclosure:

... gains financially from product or procedure presented, ... is employed by a for-profit company with an interest in the subject of the presentation, ... has significant investment interest in a competing company, ... has significant investment interest in a company producing, developing or supplying product or procedure presented