Posters

Normal reference ranges of optical coherence tomography parameters in children

Poster Details

First Author: S.Krumova BULGARIA

Co Author(s): V. Marinov   N. Sivkova   D. Koleva-Georgieva              

Abstract Details

Purpose:

To measure the macular thickness, macular volume and peripapillary retinal nerve fiber layer (RNFL) in healthy Caucasian children using spectral domain optical coherence tomography (SDOCT) and analyze the correlation of these values with age, refraction, and biometric masurements.

Setting:

In this cross-sectional study were recruited 270 healthy children (150 female, 120 male) aged 6 to 17 years with no ocular abnormality. This study was undertaken in a high school in December 2018 year.

Methods:

A detailed eye examination was performed on all children. The measurements were obtained by the use of a SDOCT devise–SOCT Copernicus REVO. Main outcome measures were macular thickness, macular volume and RNFL thickness. Their correlations with age, refractive error, anterior chamber depth (ACD) and axial length (AL) was analyzed. Right eyes of all subjects were selected for analysis.

Results:

In this study group, with mean age of 10.70 ± 2.82 years, the average peripapillary RNFL thickness was 117.11 ± 9.15µm, the central macular thickness was 232.10 ± 15.81µm.Central macular thickness, inner macular thickness (superior, nasal, temporal quadrants) values, total macular thickness and macular volume were significantly higher in males. We found positive correlation between central macular thickness, inner nasal macular thickness, outer inferior macular thickness values and age. We found a significant correlation between the average macular thickness values and the average macular volume values (p = .0001). Almost all macular parameters were consistently positively correlated with spherical equivalent.

Conclusions:

This study established normal reference ranges for RNFL and macular parameters measured by SOCT Copernicus REVO in healthy Caucasian children 6–17 years of age. This normative values could be very useful in the early diagnosis and monitoring of optic neuropathy, glaucoma and macular diseases in childhood.

Financial Disclosure:

None