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Effect of vancomycin on Bacillus cereus isolated from cataract surgery candidates

Poster Details


First Author: S.Kivanc TURKEY

Co Author(s): B. Akova   M. Kivanc                 

Abstract Details

Purpose:

To determine the effect of vancomycin under the minimum inhibitory concentration on Bacillus cereus isolated from cataract surgery candidates.

Setting:

Eskisehir Technical University, Faculty of Science

Methods:

Biofilms were determined in 96-well cell culture plates. Biofilm stained a crystal violet 2% and optical density was recorded 570 nm wavelength to estimate the biofilm density. The number of bacteria and time-kill studies were made on selected isolates.

Results:

Some strains to show increased biofilm density at vancomycin concentrations approaching the minimum inhibitory concentration. This increased biofilm density may be associated with the presence of a more resistant population. After biofilm has formedĀ  Vancomycin at MIC concentrations did not show effect.

Conclusions:

The demonstration that low concentrations of vancomycin may increase the density of newly forming B cereus biofilms; may indicate an area of potential concern in the use of vancomycin in eye.

Financial Disclosure:

None

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