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Clinical outcomes of intense pulsed light therapy in patients with meibomian gland dysfunction

Poster Details


First Author: N.Karim MOROCCO

Co Author(s): F. Benothmane   M. Chahbi                 

Abstract Details

Purpose:

To assess the clinical efficacy and safety of the intense pulsed Light (IPL) therapy in eyes with meibomian gland dysfunction.

Setting:

This work was conducted at "clinique de l'oeil" casablanca; morocco

Methods:

A randomized study was conducted on 118 eyes corresponding to 59  patients with meibomian gland dysfunction. The study compares two group: (A) combination of IPL and standard treatment; (B) standard treatment alone.Pulsed laser light (Intense Pulsed Light Regulated [IRPL®]) was use to stimulate the secretion of the Meibomian glands during 3 sessions: Day 0, day 15, day 45. Parameters were evaluated before and during treatment as well as at 1, 3, 6 and 12 months after the last treatment session. Measured parameters included the ocular surface disease index (OSDI), noninvasive breakup time (NIBUT), fluorescein breakup time (BUT), lipid layer grade, lipid layer thickness (LLT), lid margin vascularity, meibum grade, meiboscore, corneal and conjunctival fluorescein staining (CFS) score, Schirmer value.

Results:

A significant improvement was observed in all ocular surface and meibomian gland parameters in 1, 3 and 6 months compared with control group (p˂0.01). however, the OSDI score, NIBUT, meibum grade don’t demonstrate a significant difference between the two groups at 12 months.

Conclusions:

This treatment can improve the outcome of meibomian gland dysfunction. On the other hand, more sessions of IPL may be required for severe dry eye and long-term effective treatment.

Financial Disclosure:

None

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