Posters

Optical coherence tomography (OCT) detected choroidal changes in type II diabetic patients and their relation to duration and control of diabetes

Poster Details

First Author: A.El Habbak EGYPT

Co Author(s): M. Awwad                    

Abstract Details

Purpose:

To detect choroidal changes in diabetic patients with type II diabetes mellitus (DM) using spectral domain OCT and their relation to duration and diabetes control.

Setting:

Retrospective, comparative, randomized, interventional study performed on 50 patients divided into 4 groups; group I 10 non-diabetics, group II 10 diabetics without diabetic retinopathy, group III 20 diabetics with non-proliferative diabetic retinopathy (10 with Diabetic Macular Edema DME and 10 without) and group IV 10 diabetics with proliferative diabetic retinopathy.

Methods:

All patients had logMAR best corrected visual acuity BCVA, Hemoglobin A1c% (HbA1c) and OCT to measure central sub-foveal and para-foveal retinal and choroidal thickness (CT). 5 macular measurements were performed; central subfield (CSF), horizontal meridian “Inner nasal (IN), Outer nasal (ON), Inner temporal(IT), Outer temporal (OT)”. CT measurements were taken at 5 points which correspond to the same macular points.

Results:

CT at studied 5 points showed statistically significant difference between groups, being thinner in groups II, III & IV compared with group I (P 0.001). Mean Subfoveal CT in those with DME is 229±39 µm and those without DME is 258±34 µm. No statistically significant difference found in CT at all points between the 2 groups. In group III HbA1c had significant effect on the 1000 µ nasal CT (P 0.043) and the 1000 µ temporal CT (P 0.019) with negative correlation. The duration of DM had  significant effect on the 1000 µ nasal CT (P 0.048) with negative correlation.

Conclusions:

CT is significantly reduced in DME. It is altered by prolonged duration and poor control of DM.

Financial Disclosure:

None