Posters

Giant palpebral tumor revealing cutaneous T lymphoma: a case report

Poster Details

First Author: Z.Chaibi MOROCCO

Co Author(s): M. Khmamouch   R. Zerrouk   F. El Asri   K. Reda   A. Oubaaz        

Abstract Details

Purpose:

The purpose of our observation is to shed light on palpebral and lacrimal gland localization in cutaneous lymphomas T CD4+. Many lymphomas may have ocular localization which may guide the diagnosis.That's why we want to highlight the value of multidisciplinary care involving anatomopathologists,ophtalmologists maxilo-facial surgeons and  hematologists to  manage correctly this severe pathology.

Setting:

The ophtalmology department of the military hospital Mohamed V of Rabat. Morroco

Methods:

we report the observation of a 40-year-old woman with no significant pathological antecedents who reported an hypertrophy of the lacrimal gland of the right eye with concomitant onset right palpebral tumefaction gradually increasing in volume. The initial clinical examination found an ulcero necrotic palpebral mass of 12 cm in diameter. The orbital mri was in favor of an ulcer-bleeding tumor process of the fronto-palpebral and jugal soft tissues extending in intra-orbital. The patient was transferred to maxillofacial surgery for resection and the anatopathological  study led to the diagnosis of cd4 + lymphoma with CHOEP chemotherapy.

Results:

Orbitopalpebral lymphoma or ocular appendages  is a rare localization of non-Hodgkin's lymphoma. It is most commonly low-grade lymphoma of malignancy including about 50% mucosa-associated lymphoid tissue  lymphoma. Clinically, the lesions are often slowly progressive and the orbital involvement is the most frequent, often leading to exophthalmia. The diagnosis is based on the histological examination of a biopsy specimen of an accessible lesion. The Different therapeutic modalities are possible, localized radiotherapy, sometimes associated with mono- or polychemotherapy; the use of targeted therapeutics such as monoclonal antibodies is being evaluated.

Conclusions:

Malignant lymphoma has an important clinical polymorphism witch causes many problems in diagnosis and can delay the treatment. Therefore, the histological examination of biopsy pieces is the key of diagnosis.

Financial Disclosure:

None