Posters

Collagen implants vs mitomycin-C in congenital glaucoma: two year results

Poster Details

First Author: A.Abd Al-Sadek Ahmed Sinjab EGYPT

Co Author(s):                     

Abstract Details

Purpose:

To determine the safety and efficacy of collagen implants as an adjuvant in combined trabeculolomy and trabeculectomy for congenital glaucoma. To compare between collagen implant versus mitomycin-C (MMC) as regards efficacy, complications and long term results.

Setting:

Department of  Ophthalmology,  Sohag University Hospital, Sohag , Egypt

Methods:

In a retrospective study, two groups were compared.All eyes had congenital glaucoma, and underwent combined trabeculolomy and trabeculectomy. Group A; 20 eyes, collagen implant was used as adjuvant.Group B; 30 eyes, MMC was used as adjuvant. Collagen implant (12*1mm) was divided into two parts, one was applied under the scleral flap, while the other was applied subconjunctival. Outcome measures were intraocular pressure (IOP), transverse corneal diameter (TCD), corneal clarity, cup/disc ratio (C/D ratio) ,refractive changes, need for anti glaucoma medication or further surgery, and postoperative complications.

Results:

Outcome measures in both groups at two years postoperative were collected and analyzed. In Group A, 15 eyes showed complete success; with IOP ranging between 9 and 14 mmHg (average 12.5) without medication and TCD (11-12.5, 11.6), clear cornea and stable refraction.4 eyes showed guarded success with IOP controlled under 16 mmHg with one medication, TCD (12-13 mm), one eye suffered failure necessitating another procedure.In Group B, 21 eyes showed complete success, 5 eyes guarded success and 4 eyes failed.

Conclusions:

Collagen implant is a safe and as effective as MMC as an adjuvant in congenital glaucoma. Failure rate at two years is less with collagen implant than MMC, however it is still statistically insignificant difference. Further studies on larger samples and longer follow up periods are required.

Financial Disclosure:

None