Posters

Rare stromal corneal dystrophic diseases: a clinical and histopathological analysis for accurate diagnosis

Poster Details

First Author: A.Reda OMAN

Co Author(s):                     

Abstract Details

Purpose:

Corneal dystrophy encirclements a heterogenous group of genetically determined corneal diseases. Many features still remain unknown. Aim: The purpose of this study was to highlight the clinical and the histopatholgical aspects of the rare stromal corneal dystrophies and to assess the clinical and the histopathological roles in their diagnosis

Setting:

its private practice of cornea patients came for Dar eloyoun eye laser center as well as referral for surgery from the governmental hospitals

Methods:

This study incorporated 10 eyes of 6 patients, clinically diagnosed as follows: 4 patients with bilateral lattice stromal corneal dystrophy (8 eyes) and two patients,  one eye with macular dystrophy and the other eye  with granular type corneal dystrophy. Histopathological examination with applications of many special stains was done in 4 eyes (4 patients) after penetrating keratoplasty

Results:

The histopathological examination was in concordance with the clinical diagnosis of  3 examined  corneas and revealed first eye with lattice dystrophy, second eye with macular dystrophy and  third eye with granular dystrophy. The fourth examined cornea was not that in concordance with the clinical diagnosis of lattice corneal dystrophy as it showed mixed stromal corneal dystrophy patterns of granular, macular and lattice types.

Conclusions:

Histopathological assessment of corneal dystrophy cases, subjected to keratoplasty  is recommended to avoid missing cases with mixed stromal corneal dystrophy. Also, using slit lamp alone  in the clinical assessment of the corneal opacity appeared to be limited mode and thus, the imaging corneal methods such as Corneal optical coherence tomography is recommended for future cases especially in cases with unclassic query diagnosis.

Financial Disclosure:

None