Posters

The usage of platelet-rich plasma for chronic corneal epithelial defects after penetrative ophthalmo-surgery in patients with diabetes

Poster Details

First Author: A.Loshkareva RUSSIA

Co Author(s): D. Maychuk                    

Abstract Details

Purpose:

To estimate effectiveness of platelet-rich plasma (PRP) instillations after surgery in patients with 1-st and 2-nd type of diabetes with previously unsuccessful treatment of corneal defects.

Setting:

Therapeutic Ophthalmology Department. Svyatoslav Fyodorov State Institution Eye Microsurgery Complex, 59A Beskudnikovskii Blvd, 127486, Moscow, Russia.

Methods:

the study included 30 diabetic patients (30 eyes) of age 58,4±7,7,  with corneal epithelial defect provoked by cataract or vitreoretinal surgery. The included patients previously to the study had one week standard reparative treatment with no positive dynamic. PRP treatment included patient’s vein blood with Sodium citrate and Dextrosa subjected to double centrifugation, 4 min. at 3500 rpm. PRP instillations were performed 6 times daily for 6 weeks. Additional therapy included Dexpanthenol 5%. Dynamic of treatment was assessed by Efron scale. As a control group the patient’s condition before treatment was used.

Results:

Index of the corneal lesion in group before treatment was 8,1±1,9 points. Full corneal epithelialization was observed in 21 patients (70% of cases) after 4 weeks of treatment and 26 patients (86,7 % of cases) after 6 weeks of treatment. 4 patients (13,3% of cases) had positive dynamic with visualized depression of corneal lesion index but did not had a full epithelialization. Index of the corneal lesion in the study group after treatment was 2,9 ±1,2 points.

Conclusions:

In comparative analysis with standard methods of therapy positive dynamic of PRP treatment was shown.

Financial Disclosure:

None