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Finger-prick autologous blood for the treatment of dry eye disease: randomised controlled trial

Poster Details


First Author: A.Hassan UK

Co Author(s): A. Hassan   S. Balal   S. Ahmad   A. Sharma           

Abstract Details

Purpose:

To investigate the use of finger-prick autologous blood as an add-on therapy for dry eye disease (DED) poorly controlled by conventional treatment alone.

Setting:

Moorfields Eye Hospital

Methods:

Randomised controlled multi-centre trial at two centres which recruited 60 patients. Control arm = 30 Treatment = 30. Patients where seen at baseline and week 4 and 8 for vision, Schirmers 1, tear break up time, OSDI and ocular surface staining grade (Oxford Schema, Bron)

Results:

Improvement in ocular surface staining grade (Oxford Schema, Bron) of 0.54 (0.27)* in right eye and 0.38 (0.24) in the left eye where seen at week 8 and OSDI Score saw a mean reduction (SE) (SD) of 18.14* (5.07) (24.83) in the intervention arm. Improvements in all clinical parameters seen, although due to the small sample size not statistically significant. *P<0.05

Conclusions:

FAB is a safe and beneficial treatment when added to conventional medical therapy for DED. No complications from treatment.

Financial Disclosure:

None

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