Posters

Ocular complications during toxic epidermal necrolysis in children

Poster Details

First Author: A.Ghazza FRANCE

Co Author(s): S. Belghmaidi   M. Zaakoun   I. Hajji   A. Moutaouakil           

Abstract Details

Purpose:

The aim of our study is to describe the mucocutaneous and ophthalmologic sequelae in children following Lyell's syndrome and Stevens-Johnson syndrome (SSJ), and to study the correlation between the severity of cutaneous and ocular involvement based on the prognostic scores of the disease.

Setting:

University hospital Mohammed VI Marrakesh

Methods:

Retrospective study in collaboration with the dermatology department, covering 16 childrens, collected over a period of 4 years, and retained in the presence of an associated ocular lesion. The severity of the disease was assessed by the Scorten score and ocular involvement by the Foster score.

Results:

The average age was 7 years old. The diagnosis was based on a cutaneous symptomatology made of bullous lesions and mucosal erosions less than 10% of the cutaneous surface in case of SJS ( 56.25%) and more than 30% in case of Lyell's syndrome (43.75%).According to Foster's classification, 7 patients were classified as stage I , 5 in SII, and 4 in SIII . Stage I consisted of 86% SJS , SII 22% SJS and 42.85% lyell while SIII included only Lyell cases correlating the degree of severity of ocular involvement with skin involvement and the prognosis of the disease.

Conclusions:

Toxic epidermal necrolysis is severe and redoubtable, hence the need for early and adequate multidisciplinary management with regular monitoring to avoid sequelae. There is a direct correlation between the severity of cutaneous and mucosal involvement and ocular involvement.

Financial Disclosure:

None