Posters

Topical cyclosporine A as an alternative to topical prednisolone for herpetic stromal keratitis

Poster Details

First Author: M.Fornella URUGUAY

Co Author(s): R. Cessio   C. Cessio                 

Abstract Details

Purpose:

To describe the case report of a 52-year-old female with glaucoma and a chronic, recurrent ocular herpes simplex virus disease who presented with a non necrotizing stromal keratitis. She was initially treated with oral antivirals and steroids, and later switched to topical ciclosporine due to elevated ocular pressure.

Setting:

British Hospital, Montevideo, Uruguay.

Methods:

Chart review of a patient who presented to the eye hospital.

Results:

The patient presented with redness, photophobia, tearing and decreased vision in her  left eye. The examination revealed a BCVA 20/40, conjunctiva hyperemia, focal cornea opacity and stromal edema; the intraocular pressure was 15 mmHg. She was initially treated with topical prednisolone 1% and oral acyclovir 400 mg/5 times a day. The symptoms and findings gradually improved, however, her intraocular pressure was 25 mmHg after 4 days of treatment. Prednisolone was replaced with topical ciclosporine 1%. Visual acuity, slit-lamp appearance and intraocular pressure significantly improved after 30 days of treatment.

Conclusions:

Herpes simplex virus non necrotizing stromal keratitis can be treated effectively with topical cyclosporine, particularly in cases where the patient is unable to use topical prednisolone.

Financial Disclosure:

None