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Limbal stem cell deficiency (LSCD): after a lime ocular burn

Poster Details


First Author: Z.Filali MOROCCO

Co Author(s): Z. Filali   J. Chaakouk   A. Bouzidi   A. Alami   S. Iferkhass   A. Laktaoui     

Abstract Details

Purpose:

The limbal stem cell deficiency is a disease in which the stem cell and the barrier function of the limbus fail which is expressed by : - A corneal conjunctivalization associated with  a persistent epithelial defects  The chemical/ thermal ocular burn is one of the most common causes of this syndrom The purpose of this presentation is to to shed the light on the need for a rapid and adequate treatment of such conditions, in order to avoid getting to the transplant, which is the treatment of last resort.

Setting:

We report here the case of a man who suffered a bilateral ocular burn by lime and who was seen in our formation.

Methods:

A 19-year-old patient, with no particular medical history ; admitted in our service after an ocular burn with lime (PH = 12.3). The initial examination found a visual acuity at ‘hand motion’ in both eyes, with a second degree burn in the right eye  and a third degree in the left one ;besides a central corneal ulcer The conduct adopted : Hospitalisation,abundant eye wash,artificial tears,AIS autologous serum, therapeutic lens The evolution was marked by the appearance of a vascular call on 360 ° in both eyes. Subsequently, the patient presented an (LSCD). The patient was then referred for corneal transplantation.

Results:

The Initial treatment must achieve three main objectives: - Prevent conjunctival invasion - Substitute the lack in LSC - Restore a limbal stromal microenvironment If the LSCD persists aftere this initial approach a  corneal transplantation may be needed And this was the case of our patient.

Conclusions:

The LSCD may occur following numerous affections of the ocular surface and in particular the ocular burns.   The initial treatment without a transplant may be favorable, but in most cases a corneal transplant is required. Hence the interest of prevention and awareness of the population regarding eye burns.

Financial Disclosure:

None

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