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Corneal infiltrates after CXL surgery procedure for progressive keratoconus

Poster Details


First Author: S.El Maroufi MOROCCO

Co Author(s): L. Bouanane   O. Filali Kamouni   A. Bennis   F. Chraibi   M. Abdellaoui   I. Benatiya Andaloussi     

Abstract Details

Purpose:

Corneal collagen cross-linking (CXL) is a safe and effective treatment protocol used to halt the progression of keratoconus (KC). Although rare, complications like haze, infectious and sterile keratitis, corneal melting, and diffuse lamellar keratitis have been reported after CXL.

Setting:

The study is made in Ophtalmology department  at HASSAN II university  HOSPITAL fez Morroco SIDI MOHAMMED BEN ABDELLAH university Fez Morroco

Methods:

We report 2 cases of corneal infiltrates that occurred after CXL surgery procedure for progressive keratoconus. Under strict sterile conditions using topical anesthesia, and following central 8 mm mechanical epithelial debridement, CXL was performed according to the standard method.

Results:

After uneventful surgery, both patients presented with severe photophobia, redness of the eye following the procedure. Slit-lamp examination showed an infectious keratitis of 3.5mm (case 1) and stromal infiltrates in the peripheral with epithelium defect (case 2). In the first case, the corneal ulcer culture was negative. A broad-spectrum antibiotic is started. The complete healing was after 6 weeks . In the case two due to the lack of pain and absence of pathogen from corneal samples, diagnosis of sterile keratitis was considered. Topical antibiotic and corticosteroid was administered. Three months after CXL slit-lamp examination showed a mild stromal scar.

Conclusions:

Both infectious and non‑infectious complications have been reported after CXL .Infectious complications including fungal, herpetic, and bacterial keratitis. Might be associate with epithelial defects, corticosteroid use, and infectious contamination of the cornea or the instruments used during the procedure. However, non‑infectious events, reported by many authors, occur mainly due to the stimulation of immunologic responses.

Financial Disclosure:

None

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