Posters

Corneal specular microscopy in the evaluation of corneal endothelium in anterior uveitis

Poster Details

First Author: S.Belgadi MOROCCO

Co Author(s): S. Belghmaidi   T. Elbaroudi   I. Hajji   A. Elmoutaouakil           

Abstract Details

Purpose:

examine the corneal endothelium, the vicinity of  retro descemetic precipitates and corneal pachymetry in uveitis by specular microscopy.

Setting:

University hospital center Mohammed VI, Marrakesh, Morocco

Methods:

We included in our study 25 patients with active and resolved unilateral uveitis. A non-contact specular microscope was used to capture endothelial images near and far from  retro descemetic precipitates. A qualitative and quantitative endothelial analysis was performed (cell size, cell density, cell morphology). Comparisons were made at the level of the endothelium reached (near and at the distance of the retro descemetic precipitates) and between the affected eye and the healthy eye (endothelium and pachymetry with the help of the OCT).

Results:

uveitis was inflammatory in 9 eyes, infectious in 6 eyes, and idiopathic in the rest of the cases. In the acute stage, retro descemetic precipitates  were observed as dense white deposits occupying a space of 2-6 endothelial cells of diameter depending on the type (granulomatous or not ). Endothelial mosaic near retro descemetic precipitates  underwent morphological changes. After resolution of the uveitis, the retro descemetic precipitates  were in the form of gaps or a small white deposit surrounded by a clear halo. The average cell density is 2300 c / mm2 +/- 300 without significant difference with the eye adelphe

Conclusions:

This study made it possible to note the various endothelial modifications observed in acute anterior uveitis and after the resolution . However a multimodal study and the use of confocal microscopy would be desirable and would better understand these morphological changes of the corneal endothelium.

Financial Disclosure:

None