Posters

Case report: unilateral Mooren ulcer revealing hepatitis C

Poster Details

First Author: H.Alaoui Ismaili MOROCCO

Co Author(s): Z. Hammoumi   I. Essemlali   R. Nasrouni   L. Maaloum   B. Allali   A. Kettani     

Abstract Details

Purpose:

Clinical manifestations , diagnosis and therapeutic modalities of Mooren ulcer in a patient who consults for a painful red eye at the  emergency Department of the 20th August 1953 Hospital in Casablanca (Morocco)

Setting:

Pediatric ophthalmology department; August 20th,1953 hospital Ibn Rochd University ,Hospital Center Faculty of Medicine and Pharmacy  , Hassan II University Casablanca (Morocco).

Methods:

We present the case of a 74 years old patient, consulting for a painful red eye associated with a decrease of the visual acuity and tearing evolving since 3 weeks We conducted a general, and an ophthalmological examination that founds(left eye): VA: 2/10 Conjunctival hyperemia, BUT<10 sec, Shirmer test: positive. marginal corneal ulcer making 5mm / 2mm, circumferential and digging, associated with diffuse SPK. nuclear cataract and posterior subcapsular Normal fundus. The ulcer was treated with antibiotics, artificial tears and without improvement

Results:

An infectious and immunological assessment was carried out: Hepatitis C serology: positive Once the diagnosis of hepatitis C confirmed topical corticosteroid therapy was initiated Hepatitis C treatment: ribavirin and interferon The evolution was marked by the improvement of the visual acuity (4/10) and healing of the ulcer with early onset of neovascularization.

Conclusions:

Mooren's ulcer is a chronic, unilateral or bilateral peripheral corneal ulceration. The exact pathophysiology is poorly known but the autoimmune hypothesis is the subject of a consensus, it would involve humoral and cellular immunity. Infrequent pathology that may compromise the visual prognosis. Hepatitis C is responsible for Mooren's ulcer by a mechanism of cross-immunity. Treatment: early with etiological treatment.

Financial Disclosure:

None