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Increased pupil diameter as a protective factor against IFIS despite epinephrine administration

Poster Details


First Author: I.Mylona GREECE

Co Author(s): M. Dermenoudi   N. Ziakas   I. Tsinopoulos              

Abstract Details

Purpose:

The purpose of this study is to assess whether a) the development of IFIS can be linked to the use of tamsulosin vs another a1-antagonist and b) pupil dilation remains a useful predictive factor, even after accounting for the protective effect of intracameral epinephrine.

Setting:

2nd Department of Ophthalmology, Medical Department, School of Health, Aristotle University of Thessaloniki

Methods:

The study included two male patient populations who received a1-antagonists treatment and underwent phacoemulsification with an option to receive intracameral epinephrine. First patient group (N = 32) had developed IFIS while the second (N=41) had not.

Results:

A stepwise logistic regression model concluded that the only significant contributors in discerning between the two patient groups were epinephrine administration and pupil diameter. The odds of getting IFIS decrease by 81% if one receives epinephrine and decrease by 60% with increased pupil diameter.

Conclusions:

Increased pupil diameter remains an important negative predictive factor in the development of IFIS, even after the administration of epinephrine, while tamosulosin use versus another a1-antagonist does not increase the risk.

Financial Disclosure:

None

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