Posters

Evaluation of corneal endothelial cell changes in diabetic patients before and after phacoemulsification surgery: a comparative study

Poster Details

First Author: F.El Alami MOROCCO

Co Author(s): D. Hamidallah   A. Khachane   A. Mchachi   L. Benhmidoune   A. Chakib   M. El Belhadji     

Abstract Details

Purpose:

Corneal endothelium abnormalities result in fluid imbalance, stromal swelling, and loss of transparency, thus impairing visual function. Recently, growing number of studies have focused on diabetic corneal abnormalities after cataract surgery and its comparison with non-diabetic patients, the results remain conflicting. Phacoemulsification causes endothelial celullar loss, il depends on the age, antérior chamber depth, hardness of the nucleus, the duration of the operative time and the use of certain cytotoxic products.The study was conducted to evaluate and compare corneal endothelial cell count density and Central corneal thickness between diabetic and non diabetic population before and after phacoemulsification surgery.

Setting:

Adult Ophthalmology department, 20 August Hospital, Ibn Rochd University Hospital , Faculty of medicine and pharmacy, Hassan II University, Casablanca. Morocco

Methods:

This is a comparative prospective study,60 candidates for cataract surgery were included: 30 patients diabetics with soft catarct and a passage in the back of the eye and 30 patients control group. Specular microscopy with endothelial cell density and morphology, central corneal thickness was performed preoperatively and 6 weeks after surgery.Patients with capsular pseudoexfoliation, preoperative endothelial count less than 2000 / mm3, treatment with antiglaucoma eye drops or previous surgery or ocular trauma were excluded. Phacoemulsification were performed with the same technique (divide and conquer) the accumulated dissipated energy as well as the duration of the intervention were recorded.

Results:

Mean preoperative count of endothelial cells was significantly lower in the diabetic group.The percentage of endothelial cell loss was similar in the diabetic group than in the non-diabetic group. Mean central corneal thickness was similar between groups throughout the follow-up period.There was no significant difference between the two groups regarding the duration of the operative time as well as the accumulated dissipated energy (p greater than 0.05).In our study, we separately studied the confounding factors: cumulative dissipated energy and operating time in a comparable population,which showed that balanced diabetes is not a risk factor for endothelial cell loss after phacoemulsification.

Conclusions:

Evaluation of endothelial cell density should be routine before any cataract surgery. We concluded that balanced diabetes is not an endothelial vulnerability factor after phacoemulsification.

Financial Disclosure:

None