Posters

Evaluation of corneal endothelial cell loss after cataract surgery in eyes with pseudoexfoliation syndrome

Poster Details

First Author: K.Abdelhamid MOROCCO

Co Author(s): D. Hamidallah   F. El Alami   A. Mchachi   L. Benhmidoune   R. Rachid   M. El Belhadji     

Abstract Details

Purpose:

Despite modern techniques and technologies of cataract surgery, the pseudo-exfoliation syndrome is a great challenge for cataract surgeons. An increased risk of endothelial cell loss may be expected in these patients following more complicated and prolonged surgery, requiring complex manipulation in the anterior chamber. The aim of our study is to compare the loss of corneal endothelial cells after phacoemulsification in patients with pseudoexfoliation syndrome (PXF) and normal controls (no-PXF).

Setting:

Adult ophthalmology department, 20 August Hospital, Ibn Rochd University Hospital Faculty of Medicine and Pharmacy-Hassan II University Casablanca

Methods:

Phacoemulsification and a monofocal intraocular lens implantation were performed on thirty patients with PXF (30 eyes) and 30 normal control patients no-PXF (30 eyes) with a grade II,III cataract density by the same technique (stop and chop) and the same experimented cataract surgeon. Specular microscopy SP1P Topcon (Tokyo, Japan) were performed in all patients to evaluate quantitave and qualitative characteristics of corneal endothelial cells  preoperatively, at 6 weeks and 3 months after surgery. Ocular biometry were evaluated with Aladdin (TOPCON. Tokyo, Japan). Statistical analysis was performed using SPSS 20 software.

Results:

Preoperative count of endothelial cells was lower in the PXF group. The effective phacoemulsification time (EPT) was similar in the two groups. Mean postoperative endothelial cell density was significantly lower in the two groups (p <0.05). The percentage of endothelial cell loss was significantly higher in the PXF group than in the no-PXF group at post-operative 6 weeks and three months.  Mean central corneal thickness was similar between groups throughout the follow-up period.

Conclusions:

We have found a significant endothelial cell loss in pseudoexfoliation syndrome. Preventive measures such as the use of dispersive viscoelastic solutions providing more endothelial protection, as well as the reduction of operating time and ultrasound energy are recommended during phacoemulsification in this patient’s profile.

Financial Disclosure:

None