Posters
Efficacy of azithromycin 1.5% eye drops on the signs and symptoms of patients with chronic blepharitis
Poster Details
First Author: Y.Altay TURKEY
Co Author(s): M. Kocamaz G. Demirok Y. Topalak P. Altiaylik Ozer A. Sengun
Abstract Details
Purpose:
To report the efficacy of azithromycin 1.5% eye drop plus eyelid hygiene and warm compresses in the treatment of chronic blepharitis.
Setting:
Ufuk University Faculty of Medicine, Department of Ophthalmology, Ankara
Methods:
Eighty-eight patients diagnosed with chronic blepharitis were randomly assigned to two groups. Both groups received azithromycin 1.5% eye drops twice daily for the first 2 days then group 1 (43 patients) followed by once daily for the next 12 days, and group 2 ( 45 patients) followed by once daily for the next 28 days. Patients were evaluated at study initiation, at the end of treatment and 1 month after the end of the treatment. At each visit symptoms and signs graded according to the severity and tear break-up time (TBUT) and Schirmer test values were recorded.
Results:
At the end of treatment all patients demonstrated significant improvements in the ocular symptoms, signs, TBUT and Schirmer��s test values from baseline. Between the groups, group 2 showed a significantly better and long-lasting improvement in terms of lid margin debris, meibomian gland (MG) expression, MG secretion scores and Schirmer��s test values.(p= 0.0001, p=0.02, p=0.01, and p=0.001 respectively)
Conclusions:
Azithromycin 1.5% eye drop in combination with warm compresses are effeective in treating the signs and symptoms of chronic blepharitis and the one month treatment duration shows better and long-lasting improvement than two week treatment duration.
Financial Disclosure:
NONE
