A new laboratory test method to investigate the biomechanical behaviour of the anterior lens capsule
Session Details
Session Title: Presented Poster Session: Complications Management in Cataract Surgery
Venue: Poster Village: Pod 1
First Author: : Z.Kiss HUNGARY
Co Author(s): : G. Sandor Z. Bocskai Z. Nagy
Abstract Details
Purpose:
Understanding the biomechanical behaviour of the anterior lens capsule is important to reduce the capsular complications during lens surgery. A new test method was therefore devised by our study group for analysis of the mechanical properties of the anterior lens capsule in a porcine eye model.
Setting:
Department of Polymer Engineering, Faculty of Mechanical Engineering, Budapest University of Technology and Economics, Budapest, Hungary and Department of Ophthalmology, Faculty of Medicine, Semmelweis University, Budapest, Hungary
Methods:
Fresh porcine eyes were evaluated on two individual days (10 eyes per day). The anterior capsule was cut around the equator. The custom-made specimen support produced by 3D printing technology consisted of two ring-shaped plastic parts. The capsule specimen was carefully clamped between the two rings. A needle connected to a force transducer, was pushed through the holes of the rings by a stepping motor at a constant speed until the capsule membrane punctured. The force required for stretching and the displacement of the needle were evaluated. The study was supported by the Hungarian Scientific Research Fund (OTKA 116189).
Results:
The distribution fo data for ultimate force (UF) and for ultimate displacement (UD) was normal in all cases (Day1 UF: 380±80 mN, p = 0,4554; Day1 UD: 1,87±0,52 mm, p=0,2644; Day2 UF 430±50 mN, p=0,3273; Day2 UD: 2,01±0,46 mm, p=0,4695; Shapiro-Wilk test). There was no statistically difference between the days for UF (p=0,1308) and for UD (p=0,5477, t-test). The shape of the elasticity curves was similar in both groups.
Conclusions:
This new laboratory method is feasible to investigate the biomechanical behaviour of the anterioir lens capsule. The entire procedure is expansible to human specimens for further examinations.
Financial Disclosure:
NONE
