Endothelial cell density and central corneal thickness evaluation with in vivo confocal biomicroscopy and anterior segment optical coherence tomography in healthy population
Session Details
Session Title: Presented Poster Session: Glaucoma and Imaging
Venue: Poster Village: Pod 3
First Author: : R.Kermedchieva BULGARIA
Co Author(s): : M. Konareva-Kostianeva N. Stoyanova
Abstract Details
Purpose:
To determine and compare central corneal thickness (CCT) and endothelial cell density (EDC) in healthy patients.
Setting:
Department of Ophthalmology, Medical University Plovdiv, Bulgaria
Methods:
The study enrolled 40 patients (80 eyes), with mean age 46,35 ± 12,36 from 30 to 70 years, 14 men (35%) and 26 women (65%). We used Anterior segment optical coherence tomography (AS-OCT, Optovue/RTVue) to measure CCT and In vivo confocal microscopy (IVCM) (Heidelberg Retina Tomograph/Rostock Cornea Module) to determine ECD.
Results:
The mean value of CCT 537±30,31μm for the right eyes and 535,83±30,04μm for the left eyes.The mean value of ECD 2732±358,13 for the right eyes and 2746±420,55 for the left eyes.According ECD there was no significant difference between both eyes(p=0,349).CCT values in both group showed significant statistic differences for the left eyes(p=0,007),and were higher in the male group.The mean value of ECD for the left eye in male group 2745±337,93,female group 2746,62±465,32 without significant difference between them(p=0,264).A correlation between CCT and age was not found(p=0,067)in contrast to ECD and age(p=0,045).
Conclusions:
There was no correlation between CCT and ECD. There was not found significant difference for CCT between both eyes (p=0,840). We found higher values of CCT in male group, statistically significant for left eyes (p=0,007). Low correlation between ECD and age was found as ECD decreased with age.
Financial Disclosure:
NONE
