Comparison of corneal sensation in fibromyalgia patients and healthy subjects
Session Details
Session Title: Presented Poster Session: Cornea II
Venue: Poster Village: Pod 2
First Author: : V.Aykut TURKEY
Co Author(s): : A. Elbay I. Cosakun
Abstract Details
Purpose:
In ophthalmology practices many patients occasionally apply to ophthalmology departments with subjective eye pain complaints look like dry eye symptoms. However tests reveal that majority of these patients have no dry eye disease. Aim of the present study is to evaluate the corneal sensation and dry eye tests in patients with fibromyalgia (FM) and compare with that of healthy subjects.
Setting:
In this case-control study, after obtaining a detailed ophthalmic and medical history and a comprehensive ophthalmic examination, the participants were divided into two groups. 36 patients with FM and no other ocular or systemic diseases were included in the study group and the control group consisted of 39 healthy volunteers.
Methods:
All the participants underwent a comprehensive ophthalmic examination including corrected visual acuity, slit lamp biomicroscopy, indirect ophthalmoscopy and intraocular pressure measurement. Furthermore, tear film breakup time (TBUT), Schirmer test, Cochet-Bonnet esthesiometer test and self-reported ocular symptoms questionnaire were performed for all participants. All the measurements were performed for right eye of each subject.
Subjects with any autoimmune disease and patients with headache caused by the diseases other than FM were not included in the study. Subjects were suffered from the diseases which might variate the corneal sensation or participants underwent any ophthalmic operation were excluded from the study.
Results:
There were no statistical differences between the groups according to Schirmer test and TBUT results. OSDI scores were higher in the study group than the controls (19.4±9.9 vs 5.5±4.02,p<0.001). Corneal sensitivity was measured as 60.0(45.0–60.0), 57.5(45.0–60.0), 53.89±5.23, 55.00±4.86, 54.44±5.14 in the central superior, inferior, temporal and nasal regions of the cornea respectivelyat at FM patients while it was 55.0(45.0-60.0) (p=0.033) in the central, 50.0(35.0–60.0)(p=0.005)in the superior, 46.03±6.71(p<0.001) in the inferior, 53.85±4.36(p=0.282) in the temporal and 53.72±4.83(p=0.530) in the nasal regions of the cornea in the control group.
Conclusions:
Corneal sensitivity and OSDI scores were found higher in patients with FM compare to healthy individuals. However Schirmer test and TBUT results did not reveal a difference between the groups. Patients who reported complaints of dry eye symptoms, which is an important factor for the assessment and treatment of dry eye, may have a central sensitivity syndrome with FM.
Financial Disclosure:
NONE
