Comparison of cataract surgery outcomes when using bromfenac or dexamethasone anti-inflammatory treatment

Session Details

Session Title: Presented Poster Session: Cataract Surgery Complications and Management

Session Date/Time: Saturday 05/09/2015 | 09:30-10:50

Paper Time: 09:50

Venue: Poster Village: Pod 1

First Author: : N.Nastase ROMANIA

Co Author(s): :    C. Tataru   A. Dogaroiu   D. Tache   S. Badescu     

Abstract Details

Purpose:

To evaluate central macular thickness (CMT) before and after uncomplicated cataract surgery in selected groups of patients and to determine the impact of antiinflamatory drugs and diabetes on it.

Setting:

Clinical Emergency Hospital of Ophthalmology, Bucharest

Methods:

The study comprised four groups of patients who received either Bromfenac 0.09% or Dexamethasone 0.1% postoperatory; 2 diabetic groups without retinopathy and 2 non-diabetic groups. All subjects underwent uncomplicated phacoemulsification by a single surgeon and received antiinfective intraoperative and postoperative standard of care. Central macular thickness was measured with spectral domain optical coherence tomography preoperatory, day 1, 4 and 30 postoperatory. We have evaluated age, sex, severity of anterior chamber reaction, intraocular tension, phaco time, best corrected visual acuities, and the impact of medications and diabetes on central macular thickness.

Results:

There was a higher increase in CMT in diabetic patients compared with the nondiabetics in day 4 and also 30 after surgery. No significant differences were noticed in CMT between day 4 and day 30 for non diabetic patients. The longer the phaco time was, the highert increase in CMT in day 1 and 4, but this didn't reach statistical significane for any group. We didn't notice any important differences in CMT between Bromfenac or Dexamethasone administration. However two patients in the diabethic dexamethasone group developed Cystoid Macular Edema. Intraocular pressure was in normal parameters in all groups.

Conclusions:

Patients with diabetes have a higher incidence of increased CMT after cataract surgery compared with the nondiabetics. Phacoemulsification time could influence the central macular thickness, but with no impact on visual acuity on long term. Treatment with topical Bromfenac appears to be as effective as topical Dexamethasone. Taking into consideration that we have administered Bromfenac twice a day and Dexamethasone four times a day, Bromfenac would be a better and more convenient solution for the patient.

Financial Interest:

NONE