Correlation of intraocular pressure reduction with preoperative relative lens position in patients with cataract and occludable angles

Session Details

Session Title: Glaucoma I

Session Date/Time: Monday 07/09/2015 | 08:00-10:30

Paper Time: 08:40

Venue: Room 10

First Author: : K.Aditya INDIA

Co Author(s): :    M. Singh   V. Gupta   M. Kapoor   N. Singh   Q. Jawaid        

Abstract Details

Purpose:

In Indian subcontinent and asia pacific region ,Angle closure glaucoma is leading cause of Ocular morbidity.Effect of Catactogenesis on pathophysiology of Angle Closure is being increasingly established. Relative Lens Position(RLP) is a sensitive indicator for Anterior Chamber Crowding since it incorporates Lens thickness,Central Anterior Chamber Depth and Axial Length. Thus in high risk patients of occludable angle i.e Posterior Trabecular Meshwork not visible in >270 degree, effect of cataract extraction on IOP reduction and its correlation with preop RLP needs to be established to establish guidelines for lens extraction as preventive strategy for progression of Angle Closure.

Setting:

This study was conducted at Dr Baba Saheb Ambedkar Hospital ,New Delhi, India. A tertiary care center situated in urban area catering to both urban and rural population.

Methods:

This randomised prospective interventional study was conducted from June 2014 to January 2015 on 50 diagnosed cases of immature senile cataract NS II or more advanced with goniocopically occludable angles i.e 270 degree of posterior trabecular meshwork not visible. Preoperative Intraoular pressure was determined by applanation tonometry and biometric measurements i.e axial length,central anterior chamber depth,lens thickness with PacScan300AP A scan RLP is calulated by formulae (ACD+0.5AL)10 / AL. Postoperative final IOP measurement was taken at day 90 apart from day 1,7,14,28. Correlation was carried out by univariate analysis.

Results:

Correlation of IOP reduction at day 90 from Preop IOp with Relative Lens Position is highly significant p<0.001 with correlation co-efficint of -0.7328.

Conclusions:

Mean IOP reduction at day 90 in patients was 3.19+/-0.79 mmHg which was highly significant p<0.0001 after initial transient rise which levels off by end of first week.

Financial Interest:

NONE