Outcomes of intrastromal donor limbal segment implantation for treatment of progressive keratoconus

Session Details

Session Title: Cornea - Surgical III

Session Date/Time: Sunday 06/09/2015 | 14:15-16:15

Paper Time: 14:21

Venue: Room 16

First Author: : M.Panes BELARUS

Co Author(s): :    S. Pozniak   N. Pozniak                 

Abstract Details

Purpose:

To assess the effectiveness of intrastromal donor limbal segments implantation for treatment of progressive keratoconus.

Setting:

Outpatient ophthalmic clinic. Ophthalmological department of Medical Centre of Minsk Tractor Plant ,Minsk, Belarus

Methods:

Twenty-two patients (22 eyes) with progressive keratoconus II-III of Amsler classification were recruited. The worst eye was treated with the transplantation of donor limbal segments in the recipient corneal stroma, while the fellow eye was left untreated as a control. All patients underwent a complete ocular examination including uncorrected and corrected distance visual acuity (UDVA, CDVA), slit lamp examination fundus examination, corneal topography and pachymetry, auto-keratometry and Anterior Segment Optical Coherence Tomography.

Results:

After three months, statistically significant improvement in the UDVA and CDVA (Оn the average on two lines for UDVA and three-four lines for CDVA) were noted. Besides corneal astigmatism decreased from 4.82 ± 2.64 to 1.7 ± 1.4 D. There were no statistically significant differences in the changes of mean spherical equivalent, pakhimetry and keratometry indicators. It can be regarded as a process stabilization. In untreated control eyes, there was a general trend towards worsening of UDVA, CDVA and corneal thickness, while corneal astigmatism was increased.

Conclusions:

Intrastromal donor segments implantation is a safe technique of keratoconus treatment. Intrastromal donor segments implantation can improve clinical and functional results and stabilize the disease.

Financial Interest:

NONE